RAF Typhoon jets have operated alongside France's air force in a combined operation against an hidden munitions depot in Syria used by the IS group, according to the UK's MoD.
The facility, identified by intelligence, was assessed as storing arms and explosives, the announcement noted, and was situated in mountains just above the ancient city of Palmyra in central Syria.
"Our aircraft utilized precision-guided Paveway IV munitions to hit a series of entry passages down to the facility... preliminary assessments indicate the objective was successfully hit," the ministry announced.
There was no indication of any civilian casualties in the attack late on Saturday and each participating jet returned to base without incident, the MoD added.
The Typhoon fighters were assisted by a Voyager aerial refuelling aircraft.
The Islamic State group - referred to as Daesh - established extremist governance over large swathes of both Syria and Iraq prior to its 2019 collapse.
"This operation shows the UK's leading role, and commitment to work closely with our partners, to eradicate any resurgence of the terrorist group and their dangerous and violent ideologies in the region," Britain's Defence Chief the minister stated.
RAF aircraft have performed overwatch operations over Syrian airspace to "forestall any attempted comeback" of IS following its defeat at the battle of Baghuz in the year 2019, the ministry said.
"I want to thank the personnel of British forces who took part in this mission for their skill and their bravery," he added. "They were among numerous British troops stationed over Christmas and New Year. This operation, to eliminate dangerous terrorists who endanger our security, shows how UK forces are ready to step up, continuously, ensuring Britain's security domestically and powerful internationally."
In December, the US military carried out what it termed a "large-scale strike" targeting IS targets in the country, after an assault resulted in the deaths of two American soldiers and a civilian interpreter in the Palmyra area.
The U.N. reports IS still boasts an estimated 5,000 to 7,000 militants in both countries.
